PGAs are compounds that were initially manufactured to treat an eye condition called glaucoma. Since a significant portion of glaucoma patients treated with PGAs experienced increased eyelash growth, these compounds were eventually studied, manufactured, and granted FDA approval for their use in stimulating eyelash growth and appearance.

I am an eye doctor and I was one of the first to research on growth of eye lashes when patient uses a prostaglandin glaucoma eye drop. It was a wonderful side effect cos it is very potent in growing eye lashes till I found out the other side effects of prostaglandin. 

• Prostaglandin analogs can cause fat cells around the eyes to shrink. 

• Related side effects include increased hyperpigmentation, hollow or sunken skin, and an increased appearance of dark circles.